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The actress and model, 56, was engaged to the Australian from September 2011 until they split in December 2013, with their relationship attracting significant media attention.
Hurley posted a series of photos on Instagram of them together, including one of them kissing on a beach.
Another shows them smiling and holding hands at a charity cricket match.
Hurley, best known for starring in the Austin Powers and Bedazzled films, wrote: "I feel like the sun has gone behind a cloud forever. RIP my beloved Lionheart @shanewarne23."
The record-breaking Australian cricketer could not be revived after being found unresponsive in his Thailand villa on Friday following a suspected heart attack.
Many celebrity friends of Warne have since paid tribute, recalling fond memories and remembering him as a "true cricket legend".
Sir Elton John shared a photo of himself with Warne and Hurley, and he referenced the death of Rod Marsh, the Australian cricketer who also died on Friday.
He wrote: "A tragic day for Australian cricket. Two legends passing is heartbreaking. I knew them both and played cricket with Rod in Perth. A very special and fearless man.
"Shane was a magical bowler and such huge fun. They were both Australians through and through, which made them so endearing.
"My sympathies to their families and loved ones."
Hurley was among those who liked his post.
© PAA 2022
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NSW has recorded 10,017 new cases of COVID-19 and a further 10 virus-related deaths.
The number of positive cases is up by 551 from Friday when 9466 people tested positive.
Health officials say there are 995 virus patients in NSW hospitals.
Of these, 45 are in intensive care.
Of the latest infections, 6622 were detected using rapid antigen kits, while 3395 came via PCR lab tests.
Almost 96 per cent of people aged 16 and over have now received a first dose of a COVID-19 vaccine in NSW and 94.4 per cent have received two doses so far.
Some 55.4 per cent of eligible people have also received a booster dose.
Meanwhile, anyone who tests positive to the virus and is isolating during the NSW floods emergency has been asked to obey orders to evacuate.
COVID-19 positive people arriving at flood evacuation centres must notify staff, wear a mask and physically distance from others.
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Australian researchers have discovered a new way some melanomas become resistant to targeted therapies, in a find that could knock out one of the killer cancer's fuel sources.
By deactivating a pathway that controls the so called metabolic switch for melanoma cells, scientists at Melbourne's Peter MacCallum oncology institute say they can delay their ability to resist treatments.
Targeting a specific gene mutation in a patient's cancer often achieves a high response rate and triggers few side effects, says the institute's Dr Lorey Smith.
In this case, the study for which she was lead author, specifically examined melanomas with a BRAF mutation, which occurs in roughly half all melanomas.
Around 80 per cent of patients who exhibit them will respond to targeted therapies at first but unfortunately these treatments don't provide a cure," Dr Smith says.
Most will ultimately relapse - the majority within a year or two - because the residual cancer in their body develops resistance to treatment.
"In some cases, there are no changes in the genetics of these cancer cells but changes in how their mRNA is processed and turned into proteins," Dr Smith said.
Essentially, the melanoma gets smarter in response to the treatment and learns how to outwit it by reprogramming the cancer cell's metabolism.
Developing this adaptive resistance allows some melanoma cells to survive and stay in the body until the coast is clear for them to start multiplying again.
By finding a new pathway that controls the cells' metabolic switch, however, Dr Smith and her colleagues were able to knock out one of the melanoma's potential fuel sources.
"Essentially, when we switch off this pathway, we're starving the cells," she said.
"We switch off the proteins the melanoma needs to adapt and develop resistance to the treatment."
This means targeted therapies would be effective for longer.
Although the focus this time is on melanoma research, Dr Smith hopes the findings can be applied to any BRAF-mutant cancer treated with such targeted therapies.
The Peter Mac team is also trying to develop a drug that directly targets the protein they found, which seems to play an important role in melanomas developing adaptive non-genetic resistance.
Meanwhile, not-for-profit Melanoma Institute Australia has launched its 11th annual campaign to raise awareness and funds to combat one of Australia's biggest killers.
This year's effort is aimed at raising $1 million to support a world-first personalised immunotherapy clinical trial for advanced melanoma.
Currently, 50 per cent of patients in this group don't respond to or develop resistance to the immunotherapy treatment which saves others.
Images: Cancer Council
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The sports world has been left in a state of shock by the news of the sudden death of the great Shane Warne.
From modern cricketing greats like England's Ben Stokes to all-time legends of the game like Viv Richards, the overwhelming reaction was that the great bowler's death at the age of just 52 on Friday seemed unthinkable.
He was still such a larger than life character that his old foes on the field who became his great friends in the TV commentary box were left stupefied.
Former England captain Michael Vaughan captured it best as he said of Warne: "Everyone wanted to be around him but ultimately he was just a normal guy who could do incredible things.
"It just doesn't feel real to be talking about someone who once was an enemy on the pitch to one who became a great friend off it.
"Shane was the greatest ever cricketer but more than that his character lit up every dressing room, comm box, bar, golf club & friendship group.
"His energy and positivity was beyond anyone I have ever known, he was loyal beyond loyal."
West Indian legend Richards, who, like Warne, was one Wisden's five cricketers of the century, said: "Unbelievable. I am shocked to the core. This can't be true... There are no words to describe what I feel right now. A huge loss for cricket."
India great Sachin Tendulkar, who alongside Brian Lara was the batsman that Warne felt was the best he'd bowled to, said simply: "Will miss you Warnie.
"There was never a dull moment with you around, on or off the field. Will always treasure our on field duels & off field banter. You always had a special place for India & Indians had a special place for you.
"Gone too young!"
Lara himself wrote on social media: "My friend is gone!! We have lost one of the Greatest Sportsmen of all time!! RIP Warnie!! You will be missed."
Another Indian batting legend Virat Kohli described Warne as the "goat" - greatest of all-time - saying: "Life is so fickle and unpredictable.
"I cannot process the passing of this great of our sport and also a person I got to know off the field. RIP #goat. Greatest to turn the cricket ball."
India's current captain Rohit Sharma, who had been leading his team in action in a Test against Sri Lanka in Mohali, tweeted: "I'm truly lost for words here, this is extremely sad. An absolute legend and champion of our game has left us."
His fellow Indian star, paceman Jasprit Bumrah said he was "shocked beyond words ... A legend of our game, an icon, and someone who revolutionised spin bowling."
Pakistan's Babar Azam, who's captaining his side against Australia in the current Test, said: "Find it hard to believe.
"Such a devastating loss for the cricket world. He literally inspired generations with his magical leg spin. You'll forever be missed."
Former Pakistan captain Shahid Afridi felt cricket "has lost what I consider a university of leg-spin bowling today."
England allrounder Stokes wrote on Instagram that it "was an honour to know and work with" Warne.
"This man is a LEGEND," he added.
The England men's team, who are in the Caribbean preparing for a three-Test series against the West Indies, stood for a minute's silence in honour of Warne before their match in Antigua.
Mike Gatting, the victim of Warne's 'Ball of the Century' at Old Trafford in the 1993 Ashes, called his old Ashes tormentor "the number one bowler ever" in Test history.
"There have been a lot of great cricketers, great spinners and great legspinners but Warnie will always be certainly, from my point of view, the number one," said the former England captain.
Image: Shane Warne Facebook & Cricket Australia
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