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There are 244 new local COVID-19 cases in NSW along with one further death.

Some 269 virus patients remain in hospitals around the state, 52 of them in intensive care.

Health officials say COVID testers processed more than 70,000 results in the 24 hours to 8pm on Saturday.

NSW is now 89.7 per cent fully vaccinated for people aged 16 and over, while 93.9 per cent have at least had one jab.

Concerns meanwhile continue over the number of new cases being detected in regional NSW.

Of 270 local infections the state added to its caseload on Saturday, some 73 were detected in the Hunter New England health district, 37 on the mid north coast, 21 in Murrumbidgee and 10 in western NSW.

The Central Coast had six cases and there were five in both the Illawarra and Blue Mountains.

Ongoing sewage surveillance also found virus fragments in samples collected from a number of locations where no cases have yet been recorded including Uralla and Byron Bay in northern NSW and at Dungog and Denman in the Hunter Valley.

With new cases beyond Sydney remaining stubbornly high, authorities are worried about the impact on Indigenous communities especially as travel around NSW resumes.

At Friday's national cabinet meeting, National COVID Vaccine Taskforce co-ordinator Lieutenant General John Frewen gave an update on the plan to partner with Aboriginal community-controlled health organisations to accelerate vaccination rollout, noting hesitancy continued to be a factor.

Doherty Institute modelling has found Indigenous communities may require localised health strategies.

Federal Labor pointed to an Indigenous "vaccination gap", including in five regions where the difference between the state's double-dose rate and the rate for fully vaccinated Indigenous people exceeds 20 per cent.

In the Richmond-Tweed, 59.9 per cent of the Indigenous population aged over 15 is fully vaccinated, while in Coffs Harbour-Grafton the figure is 63.5 per cent.

The NSW mid north coast has 63.7 per cent, New England 66.2 per cent and Murray 67.2 per cent.

© AAP 2021

Another 244 local COVID-19 cases have been reported in NSW along with one death, an unvaccinated man from the southern border region.

NSW Health on Sunday confirmed the man in his 60s from Albury died at Melbourne's Box Hill Hospital. He was unvaccinated.

His death brings the state's toll throughout the pandemic to 593, with 537 of those recorded since June 16.

It comes as COVID-19 continues to spread in regional NSW, with more than half of new infections outside Sydney.

Of the 244 local cases, 77 were detected in the Hunter New England health district, 20 on the mid north coast, 17 in Murrumbidgee and nine in western NSW.

Four cases were from the Central Coast, three in southern NSW and two in the Blue Mountains, while another was found in a "correctional setting".

Virus fragments were also detected in samples collected from other regional areas where there are no recent known cases, including Bermagui, Moruya, Young, Gulargambone and Cobar.

Anyone in these areas with symptoms is urged to immediately get tested and isolate until they receive a negative result.

Some 269 virus patients remain in hospitals across the state, 52 of them in intensive care.

Health officials say COVID-19 testers processed more than 70,000 results in the 24 hours to 8pm on Saturday.

NSW is on the brink of hitting its 90 per cent full vaccination target for people aged 16 and over, with 89.7 per cent now double dosed.

Of the 12- to 15-year-old age group, 80.1 per cent have had their first dose and 68.6 per cent both.

© AAP 2021

Sydney's mass COVID-19 vaccination hub at Qudos Bank Arena will be closed as NSW turns its attention to booster shots.

NSW Premier Dominic Perrottet announced the centre would close its doors on Sunday after delivering more than 360,000 vaccine doses since opening on August 9.

The arena will return to hosting sport and entertainment events.

Mr Perrottet said it was an important milestone in the state's vaccination program, as it transitions to giving booster shots to adults who received their second jab at least six months previous.

"It is very clear that this booster program here in our state is going to be critical in order to keep people safe and ensure we can keep NSW open," he told reporters while touring the new Granville Centre vaccination clinic, which will open on Monday.

NSW is on the brink of hitting 90 per cent full vaccination of people aged 16 and over, with 89.7 per cent now double-dosed.

Health Minister Brad Hazzard said the closure of the arena would not further slow the state's vaccination rate.

"We're now in the tougher end of the vaccination (program) ... where people who have been reluctant for a variety of reasons are now contemplating whether or not they should be vaccinated," he said.

"They are coming forward but they're coming forward more slowly."

It comes as another 244 local COVID-19 cases were reported in NSW along with one death, an unvaccinated man from the southern border region.

NSW Health on Sunday confirmed the unvaccinated man in his 60s from Albury died at Melbourne's Box Hill Hospital.

His death brings the state's toll throughout the pandemic to 593, with 537 of those recorded since June 16.

Some 269 virus patients remain in hospitals across the state, 52 of them in intensive care.

COVID-19 continues to spread in regional NSW, with more than half of new infections outside Sydney.

Of the 244 local cases reported to 8pm on Saturday, 77 were detected in the Hunter New England health district, 20 on the mid north coast, 17 in Murrumbidgee and nine in western NSW.

Four cases were from the Central Coast, three in southern NSW and two in the Blue Mountains, while another was found in a "correctional setting".

Virus fragments were also detected in samples collected from other regional areas where there are no recent known cases, including Bermagui, Moruya, Young, Gulargambone and Cobar.

Anyone in these areas with symptoms is urged to immediately get tested and isolate until they receive a negative result.

© AAP 2021