Prime Minister Anthony Albanese has tested positive for COVID-19 for a second time and gone into isolation.

"This afternoon I had a routine PCR test which has returned a positive result for COVID-19," Mr Albanese said on Monday.

"I encourage anyone who is unwell to test and to take any extra precautions to keep their families and neighbours well."

The prime minister is at Kirribilli House and is up to date with his booster shots.

Mr Albanese is expected to take part in a national cabinet meeting on Wednesday and is planning a trip to Papua New Guinea next week.

© AAP 2022