Prime Minister Scott Morrison will continue to campaign as his opponent Anthony Albanese is forced into isolation after testing positive for COVID-19.
While wishing Mr Albanese well, the prime minister says 50,000 Australians catch the virus every day and continue on with their lives.
"You just get on with it," Mr Morrison told the Seven Network.
"When I had COVID ... we had Quad meetings, major presentations and I'm sure (Mr Albanese) will be able to do that from his home in Sydney.
"Hopefully the symptoms aren't too bad but I wish him a speedy recovery."
Senior Nationals senator Bridget McKenzie said "the stakes are very high at the moment" when asked whether the coalition has an advantage.
"We've got a strong campaign and a strong proposition for the Australian people," she told the ABC.
The Labor leader returned a positive result following a routine PCR test on Thursday afternoon, but is not showing symptoms.
Mr Albanese was due to fly out on Friday from Sydney to campaign in Western Australia.
He will instead isolate at his home in Sydney for seven days.
"While at home I will continue my responsibilities as alternative prime minister and will be fighting for a better future for all Australians," he said.
"I am grateful to know that I will have access to the world's best health care if I need it, because of Medicare."
Labor campaign heads had prepared for the possibility Mr Albanese might test positive, with opposition frontbenchers set to play an expanded role over the coming days.
Mr Albanese is likely to still conduct press conferences virtually, should he not be experiencing COVID-19 symptoms.
Deputy Leader Richard Marles says Labor will continue to sell its message while logistics will be managed on a day-to-day basis.
"Commitments will change. Albo was intending to be in Perth today and tomorrow. That is obviously not happening," he told the ABC.
"The message doesn't change. It is just making sure that we get the same message out there.
"There will be an opportunity, with technology today, to still have Anthony's voice out there articulating the messages that we want articulated."
ALP national president Wayne Swan said Labor had "war-gamed for this".
"We've got a really talented frontbench team that can be on the job and out in the public," he told the Nine Network.
"There's an enormous amount that Albo can do from isolation. So I don't think it's surprising. We will continue to hold the government to account on its negligence, particularly in terms of foreign policy and defence, but we'll also continue to outline our policies for the future."
Labor's campaign launch, set down for May 1 in Perth, is expected to go ahead as planned.
Mr Morrison will start day 12 of the campaign in Queensland, where he will announce a $428 million upgrade to four defence force air bases.
Construction at Amberley, Richmond, Pearce and HMAS Albatross would create 600 new jobs, with the upgrades to be completed by 2024, News Corp reports.
The Australian Electoral Commission will also conduct the ballot draws at midday on Friday for all lower and upper house seats.
The electoral commissioner confirmed 96.8 per cent of the eligible population will be able to cast their ballot when Australia goes to the polls on May 21.
More than 17.2 million people are on the electoral roll, an increase of more than 804,000 since the last election in 2019.
Electoral commissioner Tom Rogers said more than 100,000 people were added to the electoral roll in the last week before the rolls closed.
"Around 80,000 young Australians aged 18-24 jumped online in the week after the election was announced, resulting in 88.1 per cent of that age cohort ready to have their say this May," he said.
© AAP 2022