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Victoria has recorded 507 new locally acquired COVID-19 cases and another fatality ahead of the release of a comprehensive plan for easing lockdown restrictions.

The death is the eleventh of the state's current outbreak, which now also counts 5262 active virus cases in total.

Health authorities said 43,441 vaccine doses were administered in the 24 hours to Saturday evening and more than 58,000 tests conducted.

Meanwhile, the state government is supporting the development of a new finger-prick test that can identify if someone is immune to COVID-19 within 20 minutes by measuring neutralising antibodies.

While the technology will not check for current COVID-19 infection, it will predict a person's immunity to new and emerging variants of the virus and identify whether someone needs a booster shot.

The test, a collaboration between the Burnet and Doherty institutes, is currently in the prototype stage.

"Other rapid tests don't measure the important 'neutralising antibodies' that block virus infection. This is the advantage of the COVID-19 NAb-Test," Doherty Institute Professor Dale Godfrey said.

Premier Daniel Andrews is expected to release the state's long-awaited roadmap later on Sunday morning, including dates for school students to return to campus and for businesses to reopen.

Late last week, about 120,000 doctors, nurses, paramedics, and allied health workers urged the state government to prioritise the health system and its workforce over easing restrictions.

Through their unions, the health workers called for "accurate modelling" on expected ambulance demand, hospitalisations, intensive care patients and deaths.

More than 200 Victorians are in hospital with the virus, 56 in intensive care, and 40 on ventilators as of Saturday.

Of those in hospital, 87 per cent had not been vaccinated, 12 per cent had been given a first dose and two people had been fully vaccinated.

On Saturday police arrested 235 people at an anti-lockdown rally in Melbourne that saw violent confrontations and officers hospitalised.

Ten police were hurt while dealing with the rally, with injuries including a broken elbow and broken nose.

© AAP 2021